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Epithalon (Epitalon) is a synthetic derivative of Epithalamin and a potential modulator of telomerase, the enzyme that maintains and protects the telomere caps at the ends of chromosomes (strands of DNA). Research suggests that Epithalon induces telomere elongation and may fight off the effects of aging as a result.
What is Epithalon?
The Role of Telomerase in the Anti-Aging Effects of Epithalon
Early research using insects and rodents revealed that epithalon can prolong life substantially. In normal, healthy fruit flies and rats, epithalon decreases mortality by 52%. In mice prone to both heart disease and cancer, epithalon prolongs life by as much as 27% compared to controls. At least part of the answer to how epithalon achieves these profound effects is via its elimination of free radicals (charged molecules that do damage to healthy tissue).
Anti-oxidant activity is not the only reason that epithalon extends life, however. There is good evidence from in vitro experiments on human somatic cells to show that epithalon activates an enzyme called telomerase. Telomerase protects telomeres, the ends of chromosomes that are critical to ensuring the health of DNA. Epithalon’s activation of telomerase leads directly to a decrease in how many errors a strand of DNA contains, supporting the notion that epithalon protects DNA from damage. In short, epithalon protects DNA from accumulating errors over time, a process that eventually leads to cell dysfunction, aging, and even cancer in some cases.
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