Description
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CJC-1295 is a synthetic analogue of growth hormone releasing hormone (GHRH) that increases plasma levels of growth hormone and insulin-like growth factor 1 (IGF-1).  DAC is an additive moiety that prolongs the plasma half-life of CJC-1295.
As a derivative of GHRH, CJC-1295 promotes the release of GH.S tudies show that a single dose of CJC-1295 increase GH levels in mice by 2-10 times. Peak GH levelsare reached approximately 2 hours after administration and the effects last for about six days. Unlikeother GH secretagogues, CJC-1295 preserves normal physiologic release of GH. That means that thenormal circadian peaks and valleys seen in GH release remain intact and that CJC-1295 is a physiologicgrowth hormone releasing factor.
What is CJC-1295 +DAC?
Description of CJC-1295 + DAC
The CJC-1295+DAC peptide was made by ConjuChem Biotechnologies up of the first 29 amino acids of GHRH combined with a DAC supplement that allows to prolong the half-life and duration of action of the peptide CJC-1295. GHRH, the growth hormone releasing hormone, has been modified several times to create analogues that would have similar effects to GHRH, since its use is limited by short duration of action. This particular GHRH analogue was created in an attempt to find a more soluble GH secretagogue that could both be easily produced in large quantities and preserve or prolong the effects of GHRH action in the body. Although CJC-1295+DAC is chemically very similar to other GHRH analogues such as Sermorelin or even more to GRF (1-29), which is the most similar to it, they are not identical. Subcutaneous administration of CJC-1295 caused in healthy adults dose-dependent increase in GH and IGF-1 levels, which was well tolerated and safe.
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