TB-500 10mg vial

TB-500 10mg vial

$89.99

TB-500 (Thymosin Beta-4) is a 43 amino acid peptide sequence. In animal models, Thymosin Beta-4 has been shown to improve blood vessel growth, regulate wound healing, decrease inflammation, and reduce oxidative damage in the heart and central nervous system. Thymosin-beta-4 has a role in protection, tissue repair, regeneration and remodeling of injured or damaged tissues. It is also of active interest in anti-aging research.

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TB-500 is a synthetic analog of thymosin-beta-4 (TB4), a regenerative peptide that is natural to most animal and human cells. TB4 is made of 43 amino acids and is central to the wound healing process, primarily through its modulation of cellular migration and promotion of vascular growth. It is released by platelets and macrophages upon injury to reduce inflammation, cellular damage, and risk of infection. TB-500 maintains the biological activity of TB4, with both linked in clinical studies to a range of therapeutic effects.

TB-500 Mechanism of Action

TB-500 is the active domain of TB-4, which has a primary role as an actin binding protein. Actin is a critical component of cell structure and makes up microfilaments. Microfilaments are responsible for giving cells their shape, protecting the integrity of cell membranes, allowing cells to move/migrate, and certain steps in cellular reproduction. Actin is also one of the primary components of muscle protein. Without actin, muscles could not contract. Actin binding proteins, like TB-4, sequester actin monomers, the individual units of actin, so that they are protected from degradation and are available for polymerization into microfilaments when needed.

What is TB-500

TB-500 is a 43 amino acid synthetic analogue of thymosin beta-4 (TB-4), which is found naturally in nearly all mammalian cells. TB-500 is known for its effects on actin protein, cell migration, and wound healing. TB-500 has been shown in animal models and in vitro studies to improve blood vessel growth, accelerate wound healing, decrease inflammation, and promote extracellular matrix production. The peptide is under current investigation for its ability to reduce oxidative stress in spinal cord injury, improve recovery following heart attack, and for its many anti-aging effects.

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